Binding: Paperback
Description: Alan Herbert has played a leading part in discovering the biological roles for a high - energy form of DN a twisted to the left rather than to the right. Both Z - DN a and the Z - RN a sensing proteins are critical for protecting hosts against both viruses and cancers. The proteins also play critical roles in the programmed cell death of aging cells. Other types of flipons exist and alter the readout of transcripts from the genome encoding genetic information by their shape rather than by their sequence. Many of these flipons are within repeat elements that were previously considered to be just genomic junk. Instead these genetic elements increase the adaptability of cells by flipping DN a conformation. By acting as digital switches the different flipon types can alter cellular responses without any change to their sequence or any damage to DN a. These highly dynamic structures enable the rapid evolution of multicellular organisms. The junk DN a in repeats also encode peptide patches that enable the assembly of cellular machines. The intransitive logic involved enhances the chance of an individual surviving a constantly changing environment. Key Features Causes us to rethink how information is encoded in the genome Changes our understanding of how our genome evolved and how we protect ourselves against viruses and cancers while sparing normal cells Shows that high energy forms of DN a such as left - handed DN a do exist inside the cell Accessible to those in academia and the general public and speaks to the next generation encouraging them to find their own path in scientific discovery The Open Access version of this book available at http://www. taylorfrancis. com has been made available under a Creative Commons Attribution - Non - Commercial - No Derivative License (CC - BY - NC - ND) 4.0 license.
Title: Flipons The Discovery Of Z - Dna And Soft - Wired Genomes
Author(s): Herbert Alan
Publisher: Taylor & Francis Ltd
Barcode: 9781032731087
Pages: 209 Pages, 23 Line Drawings, Color; 16 Line Drawings, Black And White; 26 Halftones, Color; 12 Halft
Publication Date: 3/27/2024
Category: Cellular Biology (Cytology)